Guardia Lombardi is a small town and comune (municipality) in the Province of Avellino in Campania, Italy. At an elevation of 998 metres (3,274 ft), it is located in Irpinia in the Apennine Mountains of Southern Italy. It has experienced a number of major earthquakes throughout its history that have devastated the town, and is considered within zone 1 of the Protezione Civile's seismic classification index, indicating very high seismicity.